Oct 28, 2025TechGlobalMedicalXpress

Oxygen deprivation heightens risk of illness by changing genes, researchers discover

Blood cells under microscope

A new study reveals that low oxygen levels in the blood can alter the genetic makeup of key immune cells, weakening the body's ability to fight infection. The findings, published by researchers, provide insight into how conditions like hypoxia might compromise the immune system.

Hypoxia, or oxygen deprivation, was found to change the genetic material of immune cells, potentially affecting their function. This discovery could have significant implications for patients with respiratory conditions, high altitudes, or other situations where oxygen levels are low.

"We found that when immune cells are exposed to low oxygen, their genes are modified in a way that impairs their ability to fight off infections," said a lead researcher. "This opens new avenues for understanding and potentially treating infections in environments with limited oxygen."

The research underscores the importance of maintaining adequate oxygen levels for robust immune health. Further studies are needed to explore specific mechanisms and potential therapeutic interventions.

Read the original article on MedicalXpress.